Smoking tied to pain in every region of the body.

  • Smuck M & al.
  • Pain Med
  • 03/10/2019

  • Kelli Whitlock Burton
  • Clinical Essentials
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Takeaway

  • Smoking was associated with pain in every region of the body among current smokers, with the strongest associations with spine, head, trunk, and limb pain.

Why this matters

  • The study is the first to identify associations between smoking and pain in specific body regions.

Study design

  • Cross-sectional, population-based nationwide survey analyzed 2370 participants from the National Health and Nutrition Examination Survey (2003-2004).
  • Funding: None.

Key results

  • There were 1054 smokers and 1316 nonsmokers.
  • Smoking was associated (P<.05 with: style="list-style-type:circle;">
  • spine (OR, 2.89; 95% CI, 2.21-3.77),
  • head (OR, 2.47; 95% CI, 1.73-3.53),
  • trunk (OR, 2.17; 95% CI, 1.45-2.74), and
  • limb pain (OR, 1.99; 95% CI, 1.45-2.73).
  • A significant relationship existed between smoking status and diabetes, osteoarthritis, and history of cardiovascular disease (P<.0001>
  • Smoking status was also associated with the history of cerebrovascular accident (P=.0019).
  • Limitations

    • Details on pain severity and duration not included.

    Coauthored with Chitra Ravi, MPharm