Remember toxic shock? It still happens

  • EClinicalMedicine

  • Elisabeth Aron, MD, MPH, FACOG
  • Clinical Essentials
L'accesso ai contenuti di questo sito è riservato agli operatori del settore sanitario italiano L'accesso ai contenuti di questo sito è riservato agli operatori del settore sanitario italiano

Takeaway

  • Increased risk for menstrual toxic shock syndrome (MTSS) is associated with >6 hours of consecutive tampon use and overnight tampon use.

Why this matters

  • MTSS is an uncommon but life-threatening illness associated with the use of vaginal tampons and other intravaginal devices.
  • Improved education may decrease the risk for MTSS.

Key results

  • 55% met criteria for diagnosis of MTSS and 45% for probable MTSS.
  • Increased MTSS risk was associated with:
    • >6 hours of consecutive tampon use: OR, 2.33 (95% CI, 1.21-4.47); and 
    • Overnight tampon use: OR, 3.22 (95% CI, 1.37-7.69).

Study design

  • Nationwide case-control study in France.
  • 55 women and girls ages 12-30 years with a clinical diagnosis of MTSS who were reported to the French National Centre for Scientific Research between 2011 and 2017 were identified and compared with a control group (n=126).
  • Main exposure was tampon use.
  • Funding: Université de Lyon and the French National Research Agency.

Limitations

  • MTSS is a rare condition.