- Obstructive sleep apnea (OSA) is associated with an increased incidence of non-Hodgkin lymphoma (NHL).
- Results are based on data from the Korean National Health Insurance Service covering more than 2 million people.
Why this matters
- OSA may be a modifiable risk factor for NHL.
- Retrospective cohort study comparing all patients aged ≥20 years who made an OSA-related claim (n=198,574), propensity age- and sex-matched with those who did not (n=992,870), during the same period (2007-2014).
- Patients and control participants were followed for the incidence of NHL.
- Funding: None disclosed.
- Follow-up was 4.8±2.3 years.
- The incidence of NHL was increased by 40% in patients with OSA vs control participants (HR, 1.40; 95% CI, 1.16-1.69).
- The HR was somewhat higher for women (1.62; 95% CI, 1.07-2.38) vs men (1.28; 95% CI, 1.03-1.59).
- The groups did not differ regarding age.
- Retrospective, observational.