- Patients with migraine treated with ginger reported significantly greater decreases in pain, nausea, and vomiting compared with those receiving a placebo.
- Results are from a meta-analysis of 3 randomized controlled trials (RCTs).
Why this matters
- Prior studies of ginger have demonstrated its analgesic efficacy for osteoarthritis, menstrual pain, and muscle pain, but research on its use to reduce migraine pain has yielded conflicting results.
- Meta-analysis of 3 RCTs with 227 migraine patients treated with ginger or placebo.
- Funding: None disclosed.
- Compared with the placebo group, patients treated with ginger reported a significantly greater decrease in migraine pain:
- Risk ratio (RR), 1.79 (P=.04).
- They also had lower pain scores at 2 hours:
- Mean difference, −1.27 (P<.00001>
- Ginger showed no notable effect on treatment response (RR, 2.04; P=.43).
- It was associated with a significant decrease in nausea and vomiting:
- RR, 0.48 (P=.002).
- Adverse events did not differ significantly between groups.
- Small number of studies with small sample sizes.