Lansoprazolo

Capecitabina
Possibile riduzione della biodisponibilità della capecitabina.

Clopidogrel
Possibile riduzione dell’attività antiaggregante piastrinica.

Erlotinib
Possibile riduzione dell’esposizione ad erlotinib.

Levotiroxina
Possibile riduzione dell’efficacia della levotiroxina.

Micofenolato mofetil
Possibile riduzione dell’esposizione ad acido micofenolico, il metabolita attivo del micofenolato mofetil.

Pazopanib
Possibile riduzione della biodisponibilità del pazopanib.

Sunitinib
Possibile riduzione della biodisponibilità del sunitinib.

Tacrolimus
Possibile aumento delle concentrazioni del tacrolimus.

Voriconazolo
Possibile aumento delle concentrazioni plasmatiche del lansoprazolo.

Warfarin
Possibile aumento dei valori serici di INR (International Normalized Ratio) e possibile potenziamento degli effetti anticoagulanti.

 Bibliografia

 Product Information: CALQUENCE(R) oral capsules, acalabrutinib oral capsules. AstraZeneca Pharmaceuticals LP (per FDA), Wilmington, DE, Oct, 2017.
 Product Information: Prevacid(R), lansoprazole. TAP Pharmaceuticals Inc., Lake Forest, IL, 11/2003.
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