- Irritable bowel syndrome (IBS) is tied to a 51% increased risk of developing COPD, especially if untreated.
- The relationship likely related to shared infection, inflammation, and microbiota factors.
Why this matters
- Clinicians may consider monitoring patients with IBS for COPD and aggressive treatment for the IBS.
- Population-based study using the Taiwan National Health Insurance system of patients diagnosed with IBS between 2000 and 2011 with follow-up for ≥1 year.
- Cumulative incidence of COPD was compared among patients with IBS (n=14,021) and unaffected, propensity-matched control individuals (n=42,068).
- Funding: Ministry of Science and Technology, Taiwan.
- IBS was associated with an increased risk for COPD (adjusted HR, 1.512; P<.0001>
- Finding was consistent across all age groups and sexes.