- Hidradenitis suppurativa (HS) is linked to slightly increased overall cancer risk, as well as increased risk for several specific cancers, according to a population-based study.
Why this matters
- These results suggest that patients with HS may need increased cancer surveillance.
- Patients with HS had increased overall cancer risk vs participants with no HS:
- Adjusted (a)HR, 1.28 (95% CI, 1.15-1.42).
- Patients with HS had increased risk (aHRs; 95% CIs) for several specific cancers:
- Hodgkin lymphoma: 5.08 (1.21-21.36).
- Oral cavity/pharyngeal cancer: 3.10 (1.60-6.02).
- Central nervous system cancer: 2.40 (1.22-4.70).
- Nonmelanoma skin cancer: 2.06 (1.12-3.79).
- Prostate cancer: 2.05 (1.30-3.24).
- Colorectal cancer: 1.45 (1.09-1.93).
- In subgroup analysis, overall cancer risk was significantly increased in males with HS compared with male control participants (1.37; 1.19-1.57), but not in females with HS compared with female control participants (1.15; 0.96-1.37).
- 22,468 patients with HS and 179,734 matched control participants from the Korean Health Insurance Review and Assessment Service database were included.
- Funding: National Research Foundation of Korea, Ministry of Health & Welfare (Republic of Korea).
- Retrospective study of a large database.