- Heart infections with drug abuse have doubled from about 8% in 2002 to about 16% in 2016.
- The group most affected is young, poor white men.
Why this matters
- With the opioid epidemic, drug abuse rates have increased, and along with them the rate of heart infections.
- Authors: these findings warrant immediate action.
- Infective endocarditis (IE) prevalence among people with drug abuse (DA) doubled from 2002 to 2016 (from 8.0% to 16.3%), with an annual percentage change (APC) of 3.5% (95% CI, 3.3%-3.6%) nationally.
- By region, the APC was highest in the Midwest at 4.9% (95% CI, 4.4%-5.4%) and lowest in the Northeast at 2.4% (95% CI, 2.2%-2.7%).
- Vs IE patients without DA, those with both IE and DA had:
- Longer hospital stays: 9 vs 7 days (P<.001 class="">
- Cardiac surgery more often: 7.8% vs 6.2% (P<.001 but class="">
- Lower inpatient mortality: 6.4% vs 9.1% (P<.001>
- They were more often young, male, and white, with fewer cardiovascular and endocrine comorbidities but greater likelihood of HCV, HIV, liver disease, and alcohol abuse.
- Analysis of data for 954,709 IE-related hospitalizations (94,350 [9.9%] with DA).
- Funding: None disclosed.
- Administrative data; some exclusions potentially led to bias.