- Patients with Hashimoto’s thyroiditis (HT) without autoimmune comorbidities are at increased risk for nonspecific rheumatic manifestations (RMs), according to a cross-sectional study.
Why this matters
- Many patients with HT complain of nonspecific RMs such as muscle pain/weakness and arthralgias, but rates and associated factors were poorly understood.
- 20% of patients with HT and 6.8% of control subjects complained of ≥1 RM (P<.001>
- In patients with HT, polyarthralgia, myalgia, primary Raynaud’s phenomenon, carpal tunnel syndrome, and sicca syndrome were the most prevalent RMs.
- 7% of patients with HT and 0.8% of control subjects had a family history of rheumatic disease (P<.001>
- In patients with HT, RMs were associated with older age (P<.001 and female sex but not thyroid functional status or vitamin d levels.>
- 500 patients with HT and 310 age- and sex-matched control individuals were analyzed for nonspecific RM prevalence and associated factors.
- Funding: None.
- Observational study design.
- Lack of follow-up data.