Early detection of psoriatic arthritis: which comorbidities are predictive with psoriasis?

  • Su YJ
  • Clin Rheumatol
  • 28/05/2020

  • Brian Richardson, PhD
  • Clinical Essentials
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Takeaway

  • In patients with psoriasis, hyperlipidemia, gout, axial spondylopathy, and allergic rhinitis are associated with psoriatic arthritis.

Why this matters

  • Early detection of psoriatic arthritis is challenging.

Key results

  • Hyperlipidemia (OR, 15.94; P=.02), gout (OR, 3.83; P=.03), allergic rhinitis (OR, 8.17; P<.01 and axial spondylopathy were associated with increased odds of psoriatic arthritis.>
  • No analyzed serological markers were significantly associated with psoriatic arthritis after multivariate analysis (anti-extractable nuclear antigens, anti-phospholipid, and anti-neutrophil cytoplasmic autoantibodies [P>.05 for all]).

Study design

  • 629 patients with psoriasis, 102 with psoriatic arthritis, were retrospectively analyzed.
  • Funding: Kaohsiung Chang Gung Memorial Hospital.

Limitations

  • Retrospective.