- More than 30% of long-term (≥5 years postdiagnosis) early breast cancer survivors have mild to severe depression compared with 24% of population-based control participants.
Why this matters
- This is one of the first studies of depression in long-term breast cancer survivors, a group often overlooked.
- Findings suggest greater depression screening of long-term survivors.
- Cross-sectional cohort of 2 German studies: CAESAR+ of breast cancer survivors (n=3010; stage I-III, 5-16 years postdiagnosis) and LINDE population control participants without breast cancer.
- Participants were screened for depression with the Geriatric Depression Scale short form (GDS-15, with scores of 0-15;
- Funding: German Cancer Aid.
- Most patients with breast cancer were aged 60-69 years (36%) and 70-79 years (32%), with only 5% aged 80-89 years.
- Long-term breast cancer survivors were more likely to report depression of any severity (30.4% vs 23.8%; P=.0003), adjusting for age and education.
- Breast cancer survivors aged ≥80 years reported severe depression less frequently than population-based control participants.
- Breast cancer survivors with recurrence reported more mild to severe depression than recurrence-free survivors and population-based control participants.
- Mild depression was more likely in patients who were younger (
- Similar determinants were found for severe depression.
- Cross-sectional, observational studies.