Chronic pain prevalent among cancer survivors

  • Sanford NN & al.
  • Cancer
  • 22/08/2019

  • Craig Hicks
  • Clinical Essentials
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Takeaway

  • The prevalence of chronic pain among cancer survivors appears high and is likely to increase with use of multiple therapies having additive or synergistic long-term toxicity.

Why this matters

  • "These findings underscore the need to raise awareness regarding the multifaceted pain experience of cancer survivors and to train providers in screening for and managing chronic pain," researchers say.

Study design

  • 115,091 U.S. participants (no cancer history, n=107,526; cancer history, n=7565) from the National Health Interview Survey were studied.
  • Funding: None disclosed.

Key results

  • Higher odds for chronic pain were noted in participants with a history of cancer diagnosis than without (30.8% vs 15.7%; aOR, 1.48; P<.001>
  • Positive association between older age (≥48 years) and chronic pain was limited to patients without cancer (aOR, 2.38; P<.001>
  • History of sarcoma was tied to the highest odds for cancer pain (aOR, 2.62; 95% CI, 1.67-4.13).
  • In participants with a history of cancer diagnosis, chronic pain was associated with greater odds (P<.001 for:>
  • Feeling depressed (aOR, 3.49).
  • Feeling worried/nervous/anxious (aOR, 2.60).
  • Missed work (aOR, 4.90).
  • Assistance needed for activities of daily living (aOR, 3.92).
  • Instrumental activities of daily living (aOR, 3.86).

Limitations

  • Cross-sectional survey without follow-up.

Coauthored with Chitra Ravi, MPharm