Children with atopic dermatitis at increased risk for mental health symptoms

  • J Am Acad Dermatol

  • Brian Richardson, PhD
  • Clinical Essentials
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Takeaway

  • Pediatric atopic dermatitis (AD) is associated with higher odds of mental disorder with impairment (MDI), according to the US National Health Interview Survey.

Why this matters

  • The effects of AD on global mental health symptoms was unclear.

Key results

  • Prevalence of MDI was 26.7% in children with AD and 17.7% in children without AD (P<.001 style="list-style-type:circle;">
  • 10.9% and 6.2%, respectively, for severe MDI.
  • AD was associated with increased odds of MDI (OR, 1.28; 95% CI, 1.14-1.44) in adjusted analysis.
    • OR, 1.46; 95% CI, 1.33-1.61 for "often worries."
    • OR, 1.24; 95% CI, 1.09-1.42 for "unhappy/depressed."
    • OR, 1.23; 95% CI, 1.13-1.34 for "poor attention span."
    • OR, 1.46; 95% CI, 1.31-1.63 for "difficulties in emotions, concentration, behavior, or getting along with others."
  • In children with AD, 13.3% of those had seen a mental health professional in the last year.
    • 19.9% of those with mild MDI and 53.5% of those with severe MDI.
  • Study design

    • A weighted total of 57,726,856 children (aged 4-17 years) from the US National Health Interview Survey, 6,807,687 with AD in the past 12 months, were analyzed for MDI prevalence.
    • Funding: National Institute of Arthritis and Musculoskeletal and Skin Diseases.

    Limitations

    • Self-reported data may have led to misclassification bias.