- Age at menopause and type of menopause likely have only a small effect on conventional cardiovascular disease (CVD) intermediates from midlife to age 69 years.
Why this matters
- Early age at menopause is associated with increased CVD risk.
- Data from this birth cohort analysis may reassure patients that the effect may be small.
- Systolic BP, diastolic BP, BMI, and waist circumference trajectories from age 36 to 69 years were not statistically different by age at menopause onset or type of menopause.
- Triglycerides, cholesterol measures, and HbA1c trajectories from age 53 to 69 years were not statistically different by either age at onset or type of menopause.
- Birth cohort study.
- Cohort was taken from the UK Medical Research Council (MRC) National Survey of Health and Development.
- Data were collected longitudinally and prospectively from age 36 to 53 years and from age 36 to 69 years.
- Conventional CVD intermediates: age at menopause, type of menopause (natural vs hysterectomy), BP, lipids, HbA1c, and BMI were examined.
- Funding: The UK MRC; individual funding to authors.
- Measures not available for all women.
- Selection bias possible.