ADA 2019—What are the optimal BP targets in T1D?


  • Emily Willingham, PhD
  • Conference Reports
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Takeaway

  • BP targets for young people with type 1 diabetes (T1D) might need to be lower than the American Diabetes Association (ADA) recommendations of 140/90 mmHg.
  • Study findings presented at ADA 2019 pinpoint 120/80 mmHg as appropriate target for ensuring reduced cardiovascular risk.

Why this matters

  • The study authors used time-weight BP measures.
  • The findings suggest that once HbA1c enters high-normal range, the focus can turn to controlling BP, the authors said in a statement. 

Key results

  • The authors identified optimal levels for reduced coronary artery disease (CAD) risk as follows:
    • Systolic BP: 120 mmHg.
    • Diastolic BP: 80 mmHg.
    • Mean arterial pressure: 90 mmHg.
  • Compared with BP

Study design

  • Pittsburgh Epidemiology of Diabetes Complications study, including 605 participants with no known CAD who were followed for 25 years. 
  • Time-updated cumulative (mmHg/year) and time-weighted BP measures were evaluated for association with CAD.
  • Funding: Not known.

Limitations

  • Observational, so residual confounding possible.
  • Findings presented at a conference without peer review.